ACTIVE PHARMA INGREDIENTS INTERMEDIATES PYRIDINE DERIVATIVES & FINE CHEMICALS
API INTERMEDIATES
Cas No Product Application
 504-02-9 1,3-Cyclohexanedione  Carvedilol
15128-52-6 1,2,3,9-tetrahydro-4H-carbazol-4-one 
 52602-39-8 4-Hydroxycarbazole 
 51997-51-4 4-(2,3-Epoxypropoxycarbazole 
1836-62-0 2-(2-Methoxyphenoxyethylamine 
64464-04-9 2-(2-Methoxyphenoxyethylamine /HCl 
 3246-03-5 N-(2-(2-Methoxyphenoxyethylbenzylamine
120606-08-8 N-(2-(2-Methoxyphenoxyethylbenzylamine HCl 
103146-26-5 4-[(4'-Dimethyl amino)-1-(4"-fluorophenyl)-1-hydroxy butyl]-3-(hydroxy methyl) benzonitrile hydrobromide Citalopram - Escitalopram 
103146-25-4 4-[(4'-Dimethyl amino)-1-(4"-fluorophenyl)-1-hydroxy butyl]-3-(hydroxy methyl) benzonitrile
717133-25-0 4-[(4'-Dimethyl amino)-1-(4"-fluorophenyl)-1-hydroxy butyl]-3-(hydroxy methyl) benzonitrile hydrochloride
59729-33-8 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile
64169-67-1 1-(4'-Fluoro phenyl)-1,3-dihydro iso benzofuran-5-carbonitrile
  5-Bromo-1-(3-dimethyl amino propyl) –1-(4'fluoro phenyl)-1,3-dihydro isobenzofuran oxalate
717133-32-9 4-[(4'-Dimethyl amino)-1-(4"-fluorophenyl)-1-hydroxy butyl]-3-(hydroxy methyl) benzonitrile oxalate
  1-(4-bromo-2-(hydroxymethyl)phenyl)-4-(dimethylamino)-1-(4-fluorophenyl) butan-1-ol oxalate
85118-27-0 1-[3-(Dimethylamino)-propyl]-1-(4-fluoro phenyl)-5-phthalan carbonitrile HCl
128173-53-5 (+)-Dipara tolouyl–d-tartaric acid salt of 4-[(4'-Dimethyl amino)-1-(4"-fluorophenyl)-1-hydroxy butyl]-3-(hydroxy methyl) benzonitrile
5407-04-5* 3-N,N'-(dimethylamino)propyl chloride Hydrochloride
5424-47-5 3-Dimethyl amino-1-(2-thienyl)-1-propanone hydrochloride Duloxetine 
13636-02-7 RS-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine
132335-44-5 S(-)-N,N-Dimethyl-3-hydroxy-3-(2-thienyl)-1-propanamine
116817-12-0 RS-N,N- Dimethyl-3-(1-Naphthalenyloxy)-3-(2-thienyl)-1-propanamine oxalate
132335-47-8 S-(+)-N,N-Dimethyl-3-(1-Naphthalenyloxy)-3-(2-thienyl)-1-propanamine oxalate
116539-55-0 (S)-(-)-3-(N-Methylamino)-1-(2-thienyl)-1-propanol
1131-01-7 2-chloro-N-(2,6-dimethylphenyl)acetamide  Ranolazine
5294-61-1 N-(2,6-dimethylphenyl)-2-(piperazin-1-yl)acetamide 
2210-74-4 2-((2-methoxyphenoxy)methyl)oxirane 
105601-04-5 α-(meta hydroxy phenyl) ethyldimethyl amine Rivastigmine
5441-61-2 α-(meta hydroxy phenyl) ethyldimethyl amine HCL
139306-10-8 S (+)-α meta hydroxy phenyl)ethyl dimethyl amine
105601-14-7) Racemic Rivastigmine hydrochloride
63720-38-7 3-(1-aminoethyl)phenol
123982-81-0 (S)- 3-(1-aminoethyl)phenol
123441-03-2 Rivastigmine Base
6306-52-1 L-Valine methyl ester hydrochloride Valsartan
2462–34-2 L-Valine benzyl ester hydrochloride
16652-76-9 L-Valine benzyl ester p-toluene sulfonate
482577-59-3 N-[(2'-Cyanobiphenyl-4-methyl)-(L)-Valine methyl ester Hydrochloride
194602-27-2 2,2-Diphenyl-2-((R)-pyrrolidin-3-yl)acetonitrile hydrobromide  Darifenacin 
134002-26-9 3-(S)-(+)-(1-carbamoyl-1,1-diphenylmethyl) pyrrolidine - L-(+)-tartrate 
943034-50-2 5-(2-chloroethyl)-2,3-dihydrobenzofuran 
127264-14-6 5-(2-bromoethyl)-2,3-dihydrobenzofuran
207557-35-5 (S)-1-(2-chloroacetyl)pyrrolidine-2-carbonitrile  Vildagliptin
  Repaglinide Intermediates
219921-94-5 (S)-3-Methyl-1-(2-piperidin-1-ylphenyl)butylamine N-Acetyl-L-glutamate  
147769-93-5 (S)-3-Methyl-1-(2-piperidin-1-ylphenyl)butylamine 
147770-06-7 (S)-Repaglinide Ethyl Ester 
762240-92-6 3-(trifluoromethyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine hydrochloride Sitagliptin
764667-65-4 1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butane-1,3-dione /(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
40546-94-9 3,4-Dihydro-6-methyl-4-phenylchromen-2-one  Tolterodine Tartrate
 124937-62-8 Methyl 3-(2-methoxy-5-methylphenyl)-3-phenylpropanoate 
 124937-73-1 3-(2-Methoxy-5-methylphenyl)-3-phenylpropan-1-ol 
124936-74-9 2-(3-(diisopropylamino)-1-phenylpropyl)-4-methylphenol (Racemic Tolterodine) 
30389-33-4 3,4-dihydro-5-hydroxyquinolin-2(1H)-one Carteolol
51781-14-7 5-((oxiran-2-yl)methoxy)-3,4-dihydroquinolin-2(1H)-one 
936-59-4 3-Chloro-1-phenylpropan-1-one  Dapoxetine Hydrochloride 
18776-12-0 3-Chloro-1-phenylpropan-1-ol 
  Racemic Dapoxetine Oxalate
1071929-03-7 Racemic Dapoxetine Hydrochloride 
119356-77-3 Dapoxetine Base  
614-19-7 3-Amino-3-phenylpropanoic acid 
607-81-8 Diethyl-2-benzylmalonate Racecadotril 
49769-78-0 Dimethyl-2-benzylmalonate 
5669-19-2 2-Benzylacrylic acid 
1738-76-7 Glycine benzyl ester P-toluene sulfonic acid  
 56341-37-8 6-Chloroindolin-2-one  Ziprasidone
 118289-55-7  6-Chloro-5-(2-chloroethyl)indolin-2-one 
87691-87-0 3-(Piperazin-1-yl)benzo[d]isothiazole
188416-27-5 2-Chloro-6-ethyl-5-fluoro-4-hydroxy pyrimidine ammonium salt  Voriconazole
137234-74-3 4-Chloro-6-ethyl-5-fluoropyrimidine
188416-28-6 6-(1-Bromoethyl)-4-chloro-5-fluoro pyrimidine
6368-20-3 Boc-D-Serine   Lacosamide 
86123-95-7 Boc-O-Methyl-D-serine 
880468-89-3 (R)-tert-Butyl 1-(benzylamino)-3-methoxy-1-oxopropan-2-ylcarbamate
196601-69-1 (R)-2-amino-N-benzyl-3-methoxypropanamide 
 6081-61-4 N-Cbz-D-Serine 
219835-31-1 (R)-N-benzyl-2-(benzyloxycarbonylamino)-3-hydroxypropionamide
118803-65-9 4-(5-Fluoro-2-hydroxyphenyl)-4-oxo-2-butenoic acid  Nebivolol 
 105300-40-1 6-Fluoro-3,4-dihydro-4-oxo-2H-1-benzopyran-2-carboxylic Acid  
99199-60-7 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid  
129101-36-6 (S)- 6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 
129101-37-7 (R )-6-Fluoro-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid 
878208-57-2 (6-fluoro-3,4-dihydro-2H-1-benzopyran-2-yl)(piperidin-1-yl)methanone 
99199-90-3 6-Fluoro-3,4-dihydro-2-oxiranyl-2H-1-benzopyran (Mixture of Two Diastereomers) 
  2-(benzylamino)-1-(6-fluorochroman-2-yl)ethanol
  N-Benzyl Nebivolol Oxalate
65473-13-4 N-Methyl-1-Naphthyl methyl amine hydrochloride  Terbinafine and Butenafine
20880-92-6 2,3:4,5-Bis-O(1-methylethylidene)-D-fructopyranose Topiramate
141109-14-4 S-(+)-2-chlorophenyl glycinemethyl ester  CLOPIDOGREL BISULPHATE
141109-20-8 S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride
  (+) – 2 – (2-Chlorophenyl)-N- [2-(2-thienyl)ethyl]glycine methyl ester hydrchloride
28783-41-7 4,5,6,7-tetrahydro thieno[3,2-c] pyridine hydrochloride
54903-50-3 4,5,6,7-tetrahydro thieno[3,2-c] pyridine
90055-48-4 Racemic Clopidogrel hydrochloride
114772-54-2 2-Cyano-4’-bromomethylbiphenyl LOSARTAN POTASSIUM
133909-99-6 Trityl Losartan
114772-55-3 2-Butyl -4-chloro-[(2'-cyanobiphenyl-4-yl)-methyl ]-5-(hydroxymethyl)imidazole
114798-26-4 (1-((2′-(2H-tetrazol-5-yl)biphenyl-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol
147126-62-3 (2S,5R)-5-Hydroxy-[1,3]-oxathiolane-2-carboxylic acid Menthyl ester (HME) EMTRICITABINE
147126-75-8 (2S,5R)-5-Fluoro cytosine-1-yl-[1,3]-oxathiolane-2-carboxylic acid menthyl ester (FCME)
11969-64-3 L-Menthyl glyoxylate hydrate LAMIVUDINE
147027-10-9 (2S.5R)-5-Cytosine-1-yl-[1,3]-oxathiolane -2-carboxylic acid menthyl ester (CME)
102625-64-9 5-(Difluoromethoxy)-2[[(3,4-dimethoxy-2-pyridinyl)methyl]thio]-1H-benzimidazole PANTOPRAZOLE SODIUM
142678-34-0 5-(Difluoromethoxy)-2[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
75560-19-3 4-(3,4-Dichlorophenyl)-3,4-dihyro-1-(2H)-naphthalenone SERTRALINE HYDROCHLORIDE
303-26-4 1-(4-Chlrodiphenylmethyl)-piperazine CETIRIZINE DIHYDROCHLORIDE
134-83-8 4-Chlorobenzhydrylchloride
86404-63-9 2,4-difluoro-2-(1H-1,2,4-triazole-1yl)acetophenone (OR)
1-(2,4-Difluoro phenyl)-2-(1H-1,2,4-Triazole-1-yl) Ethanone
FLUCONAZOLE
  [2(2,4-difluorophenyl)-1-(1H-1,2,4-triazole-1-yl)2,3 epoxy propane methane sulphonate
  2-Carboxyethyl-3-cyano-5-methyl hexanoic acid ethyl ester PREGABALIN
  3-Aminomethyl-5-methyl haxanoic acid (racemic Pregabalin)
  3-Carbamoylmethyl-5-methyl-hexanoic acid
136522-35-5 Aminocarbinol [(1s.Cis)-4-amino-2-cyclopenten-1-methanol] ABACAVIR
171887-03-9 N-(2-amino-4,6-dichloro-5-pyrimdinyl)formamide
  (-) 1-(4-Chlorophenyl)phenylmethyl amine LEVOCETIRIZINE DIHYDROCHLORIDE
  (-)-1-(4-chlorophenylmethyl)-piperazine
  Methyl 4-(bromomethyl)-2-biphenyl-2-carboxylate  TELMISARTAN
  Trityl Olmesartan  OLMESARTAN MEDOXOMIL
152460-09-8 N-(2-Methyl-5-nitrophenyl)-4-(3-pyridyl)-2-pyrimidine Amine Imatinib mesylate
152460-10-1 N-(5-Amino-2-Methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine
106261-49-8 4-(4-Methyl piperazine-1-yl)methyl benzoic acid di HCl
106261-64-7 4-(4-Methyl piperazine-1-yl)methyl benzoyl chloride di HCl
120511-72-0 2-[3-(Cyano-Dimethyl-methyl)-5-methyl-phenyl]-2-methyl propionitrile Anastrozole
27387-31-1 1,2,3,9-Tetrahydro-9-methyl-4(H)-Carbazol-4-One Ondansetron
119812-29-2 3-[(Dimethylamino)methyl]-1,2,3,9-tetrahydro-9-methyl-4H- carbazol-4-one HCl
22990-19-8 (+/-)-1-Phenyl-1,2,3,4-Tetrahydro Isoquinoline Solifenacin Succinate
118864-75-8 (S)-1-Phenyl-1,2,3,4-Tetrahydro Isoquinoline
118864-75-8 (S)-1-Phenyl-1,2,3,4-Tetrahydro Isoquinoline
84163-42-8 N-Formyl IsoNipecotic Acid Risperidone / Paliperidone
135634-18-3 2,4-Difluoro phenyl (4-Piperidinyl)Methanone Oxime HCl Risperidone / Paliperidone
84163-77-9 6-Fluoro-3-(4-piperadinyl)-1,2-benzisoxazole Risperidone / Paliperidone
84163-13-3 4-(6-Fluoro-1,2-benzisoxazole-3yl)-piperidine HCl Risperidone
84163-13-3 4-(6-Fluoro-1,2-benzisoxazole-3yl)-piperidine HCl Risperidone
     
625120-81-2 3-(N-Methyl-N-Pentyl amino)propionic acid HCl Ibandronate sodium
105462-24-6 (1-Hydroxy-2-(3-pyridinyl)ethylidine)-1,1-bisphosphonic acid Risedronate sodium
14047-28-0 R-9-(2-Hydroxy Propyl)adenine Tenofovir
87266-37-3 Imidazole-1yl-acetic acid Hydrochloride Zoledronic Acid
147687-17-0 9-(Benzyloxy)-3-(2-Chloroethyl)-2-Methyl-4H-Pyrido[1,2-A] Pyrimidin-4-one Paliperidone
130049-82-0 3-(2-chloroethyl)-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a] pyrimidin-4-one
62780-89-6 1-(3-chloro propyl)-1,3-dihydro-2H-benzimidazol-2-one Oxatomide
22990-19-8 (+/-)-1-Phenyl-1,2,3,4-Tetrahydro Isoquinoline Solifenacin Succinate
118864-75-8 (S)-1-Phenyl-1,2,3,4-Tetrahydro Isoquinoline (Grade-2)
118864-75-8 (S)-1-Phenyl-1,2,3,4-Tetrahydro Isoquinoline (Grade-1)
42437-96-7 (R)-(-)-3-Quinuclidinol hydrochloride
180468-42-2 (S)-ethyl 1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
25333-42-0 (R)-(-)-3-Quinuclidinol
88720-45-0 (+/-)2-(2-Chlorophenyl) Glycine Methyl Ester( Recimic Mixture) CLOPIDOGREL
141109-14-4 (+)2-(2-Chlorophenyl)Glycine Methyl Ester (Tartrate Salt)
141109-19-5 (+)2-[2-Chloro Phenyl]-N-[2-(2-Thienyl)Ethyl]Glycine Methyl  Ester Hydrochloride(COUPLE AMINE HCL)   
25270-30-2 Methyl alpha –Bromo-2-chloro-phenyl acetate
90055-45-4 Racemic Clopidogrel HCL
28783-41-7 4,5,6,7- Tetrahydro Thiopheno[3,2-c]pyridine HCL Also used for[Candesartan, Prasugrel]  [ ROUTE - 1]
85259-19-4 2-Bromo -2(chlorophenyl)acetic acid methyl ester  [ ROUTE - 1]
120202-08-8 Clopidogrel Camphor Sulfonate  [ ROUTE - 1]
141109-17-3 D(+)-chloro phenyl glycine methyl ester  [ ROUTE - 2]
40412-06-4 2-Thiophene Ethanol Tosyl Ester [ ROUTE - 2]
141109-25-3 (+/-) Alpha Bromo(2-Chlorophenyl) acetic acid
137-07-5 2-Amino Thiophenol DILTIAZEM
42399-49-5 Cis (+) Hydroxy Lactum
134071-44-6 Cis Toyslate
61397-56-6 Cis Bromo Benzoate  [ALSO USED FOR KETACONAZOLE , TERCONAZOLE] ITERACONAZOLE
134071-44-6 Cis Toyslate
78-76-2 2-Bromo Butane
350-03-8 3- Acetyl Pyridine [ALSO USED FOR IMATINIB / TELITHROMYCIN ] RESIDRONATE SODIUM
6419-36-9 3-Pyridyl Acetic Acid hcl 
105462-24-6 Residronic Acid
303-26-4 (-)1-(4-Chlorophenyl) Phenylmethyl amine LEVOCITRIZINE
  (-)1-(4-Chlorophenyl methyl) Piperazine
1492-24-6 (S)-(+)-2-Aminobutyric Acid LEVATIRACETAM
7682-20-4 (S)-2-Aminobutyramide Hydrochloride
142-08-5 2-Hydroxy Pyridine
77668-42-9 2,3-Di Chloro benzoyl cyanide LAMOTRIZINE 
  Schiff’s base
7305-71-7 2-Amio-5-Methyl Thiazole MELOXICAM 
35511-15-0 Isopropyl-4-Hydroxy-2-Methyl-2H-1,2-Benzisothiazole-1,1-Dioxide-3-carboxylic acid ester ( Int Piroxican)
24683-26-9. 4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethyl ester 1,1-dioxide. 
112811-72-0 1-Cyclopropyl-7[S,S)-2,8-dizabicyclo[4,3,0]non-8-yl]-6-Fluoro-8-methoxy-1,4-dihydro-4-oxo-quinaline carboxylic acid MOXIFLOXACIN HYDROCHLORIDE
18184-75-3 6-Benzyl-5H-Pyrrolo[3,4b] pyridine-5,7(6H)dione
128740-14-7 6-Benzylo-octahydropyrrolo[3,4b] Pyridine 
138564-58-6 2 -Amino-5-methylthiophene-3-carbonitrile OLANZAPINE 
138564-59-7 2-(2-Nitroanilino)-5-methylthiophene-3-carbonitrile
138564-60- 4-Amino-2-methyl-10H-thieno-[2,3-b][1,5]-benzodiazepine hydrochloride (CRUDE)
  4-Amino-2-methyl-10H-thieno-[2, 3-b][1,5]-benzodiazepine hydrochloride [ PURE ]
93963-62-7 5-Di Fluro Methoxy-2-Merlapto Benzimidazole PENTOPROZOLE SODIUM 
72830-09-2 2-Chloromethyl-3,4-Dimethoxy Pyridine Hcl (Chloro Compound)  
102625-64-9 5-9Difluoromethoxy)2{(3,4-dimethoxy-2-pyridinyl)methyl}thino}-1H-benzimidazole [ Pantoprazole Sulphide]  
  1,3-Bis(2-Acetyl 1,3-Hydroxy phenoxy)-3- Hydroxy propane SODIUM CROMOGLYCATE
  Di Methyl ester of ( 5,5-(2-Hydroxy trimethylene dioxy) bis(4-oxo-chromene)-2- Carboxylic Acid
585-79-5 M-Bromo Nitro Benzene TRAMADOL HCL
  (1R, 2R)-2-(Dimethylamino)methyl cyclohexanone Hcl
  (1R, 2R)-2-(Dimethylamino)methyl-1-(3,methoxy phenyl) cyclohexanone
50-89-5 5'-Trityl-2'-deoxy-2,3'-di dihydro Thymidine
  5'-0-Trityl thymidine ( TritylThymidine Compound) ( TTC) ZIDOVUDINE
5964-41-0 2,3-Anhydro-5-O-trityl thymidine
  Trityl Zidovudine
  Trityl Azido Compound- TAZC
35150-07-3 N-Boc-Prolinamide -
 7531-52-4 L-Prolinamide -
15761-39-4 N-Boc-L-Proline  -
 1193-55-1 2-Methyl cyclohexane 1,3-dione  -
3014-80-0 L-Valinamide HCl  -
13811-71-7 Diethyl-D-tartrate   -
2491-20-5 L-Alanine methyl ester HCl  -
2133-40-6 L-Proline methyl ester HCl  -
 112346-82-4 (S)-3-Chloroalanine methyl ester hydrochloride  -
65732-69-6 (S)-Pyrrolidine-2-carbonitrile hydrochloride  -
5874-57-7 D-Serine methyl ester hydrochloride  -
95715-85-8 N-Boc-D-serine methyl ester  -
4251-63-2 1(2-(2-chlorophenyl)acetaldehyde  -
150736-72-4 N-Boc-(S)-(-)-2-amino-1-butanol  -
13734-41-3 N-Boc-L-Valine  -
1148-11-4 N-Cbz-L-Proline  -
 1149-26-4 N-Cbz-L-Valine -
17026-42-5 (+)-O,O'-Dibenzoyl-D-tartaric acid monohydrate (CAS Number : 80822-15-7).anhydrous -
2743-38-6 (-)-O,O'-Dibenzoyl-L-tartaric acid monohydrate (CAS Number : 62708-56-9).anhydrous  -
32634-66-5 (-)-O,O'-Di-p-toluoyl-L-Tartaric acid Monohydrate (CAS Number : 71607-31-3). anhydrous -
32634-68-7 (+)-O,O'-Di-p-toluoyl-D-Tartaric acid Monohydrate (CAS Number : 71607-32-4). anhydrous -
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